having no money, home, or job, and living on the streets
After losing his job, he became down and out and had to sleep in the park.
失業後,他變得身無分文、無家可歸,不得不在公園裡過夜。
sure to lose or fail
The team was down and out after the star player got injured.
在明星球員受傷後,這支隊伍註定要失敗了。