refractory
🇺🇸
/rɪˈfræktəri/
🇬🇧
/rɪˈfræktəri/
Not easily managed or trained; stubborn
The refractory child refused to listen to his parents.
那个顽固的孩子拒绝听从他的父母。
Resistant to treatment or not responding well to it
The doctor said the cancer was refractory and did not respond to the usual treatments.
医生说癌症是难治的,没有对常规治疗做出反应。