refractory
🇺🇸
/rɪˈfræktəri/
🇬🇧
/rɪˈfræktəri/
Not easily managed or trained; stubborn
The refractory child refused to listen to his parents.
頑固な子供は親に耳を傾けなかった。
Resistant to treatment or not responding well to it
The doctor said the cancer was refractory and did not respond to the usual treatments.
医者は、癌が難治性であり、通常の治療に反応しないと述べました。